An e-book of interest has been issued:
To characterize biopharmaceuticals, particularly monoclonal antibodies and antibody-drug conjugates (ADCs), you need a complete toolbox of powerful tools.
The key points:
- How light scattering works
Current uses of light-scattering, such as:
Determining absolute molecular weight
Studying PEGylated proteins
Characterizing antibody-drug conjugates
Studying protein aggregation
When to use light-scattering detection, and when to use mass spectrometry
Why you should consider light-scattering to determine the drug-antibody ratio of antibody-drug conjugates, and for effective characterization of the chemical, thermal, and colloidal stability of ADCs